17 Comments
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Next Step Remodel's avatar

Amazing stuff. A must read for me everyday. Thanks AWG.

Michael Amicangelo's avatar

Thank your Sir for all you do. We deeply appreciate your efforts your intelligence and your wicked sense of humor. The budding music occupation is promising

Jim Carcioppolo's avatar

Semaglutide study fascinating. If anti-aging true will definitely cut into Big Pharm/Hospital profits...and so will be downplayed and ignored.

KPK18's avatar

There will always be a market for preventative drugs. People may still get syndromes despite longevity increases -- cancer in some form will always be with us -- and we will need drugs to stop it.

Epigenetic programming will be the next great big Pharma market.

Tom's avatar

Big Pharma invented the drugs. They are making billions, soon trillions. Hospitals become Longevity Centers. Everyone wins.

Liz McClanahan's avatar

Thank you ALL , very much.

Tyler Stobie's avatar

Waiting for my AWG model to chat with all day

Rich's avatar

Let me go to the dark side. If we are the cusp of “aging backwards,” won’t life as be know it, already precious, become an even more precious commodity? And, won’t the taking of life become a more egregious crime? How will this affect capital punishment, war, and other dangers.

Erik Hochstein's avatar

So many parts - not even sure if it’s dark side … let’s say we do actually reverse and solve it - so is our population going to double quickly ? No more inheritance … will children still be “needed” ? Are we changing our one true purpose in humanity - natural evolution?

Tom's avatar

I vote for less children at the luxury anti-aging resorts. And less capital punishment, it never worked as a deterrent and its very expensive to kill a person, the figure I heard years ago was $15 million. If we can solve aging, we can solve anti-social violent behavior.

Marco Tirotta's avatar

Great article. Loved it. I'll be looking for more on subject...

Thank you!

Valerian Texeira's avatar

Singularity debugging the debugger!

Tom's avatar

@AWG Do you use a Claude Skill or agent to write your blog posts, or at least rough draft them? Would you be willing to share the skill? git repo?

KPK18's avatar

Alex says he writes The Innermost Loop himself. I would, however, ask him if a Frontier model feeds him the latest news in bio, robotics, chips, ai applications, etc. and he assembles those with his idiosyncratic and amusing prose style.

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Erik Hochstein's avatar

We will need AI to truly give us real answers — hoping and believing it’s all “there” to be solved - BUT I would never trust just pharmaceutical companies…